Intercalative Nanohybride of Cordycepin in Layered Double Hydroxide

Abstract：A novel negatively charged cordycepin-[Mg-Al-NO] nanohybrid has been prepared by ion-exchanged method.Results of TEM, PXRD and FT-IR spectroscopy confirmed that cordycepin could be intercalated into [Mg-Al-NO3] interlayers as the charge-compensating species.Preliminary result show that the new bioinorganic nanohybrid may be used as a novel inorganic pharmaceutically active compounds reservoir or carrier.b.

Keywords：cordycepin; layered double hydroxide; nanohybrid; intercalate

蟲草素LDH插層納米復合體

楊親正　 羅珊珊　 凌建亞　 李彥　 張長鎧　

摘　要：通過離子交換反應制備了一種新型蟲草素層狀雙氫氧化物納米復合體. 透射電鏡、X-衍射和紅外光譜分析結(jié)果表明,帶負電的蟲草素中和無機層片電荷而插層到鎂鋁層狀雙氫氧化物[Mg-Al-NO3]中.實驗結(jié)果顯示,通過簡單的離子交換,可制得新型生物有機納米復合體,該類納米復合體將有可能成為生物活性分子的貯存庫或載體.

關(guān)鍵詞：蟲草素; 層狀雙氫氧化物; 納米復合體; 插入

CLC Number：S567.3+5

Author Resume：Yang Qinzheng,mail,born in 1975,Ph.D..Address:State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100.張長鎧,Corresponding author

Author Unit：楊親正（山東大學微生物技術(shù)國家重點實驗室,濟南,250100）　

　　　　　羅珊珊（山東大學微生物技術(shù)國家重點實驗室,濟南,250100）　

　　　　　凌建亞（山東大學微生物技術(shù)國家重點實驗室,濟南,250100）　

　　　　　李彥（山東大學微生物技術(shù)國家重點實驗室,濟南,250100）　

　　　　　張長鎧（山東大學微生物技術(shù)國家重點實驗室,濟南,250100）　

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華中農(nóng)業(yè)大學學報

JOURNAL OF HUAZHONG AGRICULTURAL UNIVERSITY

2004 Vol.23 No.1